ENOS-INDUCED VASCULAR BARRIER DISRUPTION IN RETINOPATHY BY C-SRC ACTIVATION AND TYROSINE PHOSPHORYLATION OF VE-CADHERIN

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Background: Hypoxia and consequent production of vascular endothelial growth factor A (VEGFA) promote blood vessel leakiness and edema in ocular diseases.Anti-VEGFA therapeutics may aggravate hypoxia; therefore, therapy development is needed.Methods: Oxygen-induced retinopathy was used as a model to test the role of nitric oxide (NO) in pathologica

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Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol

BackgroundAlcohol misuse, binge drinking pattern, and gender-specific effects in the middle-aged population has been clearly underestimated.In the present study, we focused on understanding gender-specific effects of alcohol exposure on the gut-liver axis and the role of gut microbiota in modulating gender-specific responses to alcohol consumption.

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PHASE CHANGES ON 4H AND 6H SIC AT HIGH TEMPERATURE OXIDATION

ABSTRACT PHASE CHANGES ON 4H AND 6H SIC AT HIGH TEMPERATURE OXIDATION.The oxidation on two silicon carbide contain 6H phase and contains 6H and 4H phases has been done.Silicon carbide is ceramic non-oxide with excellent properties that potentially used in industry.Silicon carbide is used in nuclear industry as structure material that developed as l

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